{"id":2629,"date":"2023-09-07T14:07:37","date_gmt":"2023-09-07T14:07:37","guid":{"rendered":"https:\/\/ctm.u-bourgogne.fr\/?page_id=2629"},"modified":"2025-11-25T17:58:42","modified_gmt":"2025-11-25T17:58:42","slug":"presentation-english","status":"publish","type":"page","link":"https:\/\/ctm.ube.fr\/index.php\/presentation-english\/","title":{"rendered":"Presentation"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"2629\" class=\"elementor elementor-2629\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-927cf20 elementor-section-full_width elementor-section-stretched elementor-section-height-default elementor-section-height-default\" data-id=\"927cf20\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;,&quot;stretch_section&quot;:&quot;section-stretched&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-f893f88\" data-id=\"f893f88\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-e7719d4 elementor-widget elementor-widget-heading\" data-id=\"e7719d4\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Center For Translational and Molecular Medecine\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b1bc1bc elementor-widget elementor-widget-heading\" data-id=\"b1bc1bc\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h5 class=\"elementor-heading-title elementor-size-small\">Director UMR1231: Pr Fran\u00e7ois GHIRINGHELLI<br>\nDeputy Director UMR1231: Pr Dominique DELMAS<\/h5>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-997859c elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"997859c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-b233102 elementor-section-full_width elementor-section-stretched elementor-section-height-default elementor-section-height-default\" data-id=\"b233102\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;,&quot;stretch_section&quot;:&quot;section-stretched&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-bb5760f\" data-id=\"bb5760f\" data-element_type=\"column\" data-e-type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-b798bb0\" data-id=\"b798bb0\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-a5f83a6 elementor-widget elementor-widget-text-editor\" data-id=\"a5f83a6\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"text-decoration: underline;\"><strong>History, structure and location of the unit<\/strong><\/span><\/p><p>The Centre de Recherche UMR1231- LNC was originally created as UMR866 \u00ab\u00a0Lipids, Nutrition, Cancer-LNC\u00a0\u00bb on January 1, 2007, and grew out of a joint program by several groups that led to the signing of a four-year contract with INSERM, the University of Burgundy and EPHE. The founding teams of the LNC Research Center come from INSERM units U498 (\u00ab\u00a0Intravascular metabolism of lipoproteins\u00a0\u00bb), U517 (\u00ab\u00a0Cell death and cancer\u00a0\u00bb), and EPI-106 (\u00ab\u00a0Epidemiology of digestive cancers\u00a0\u00bb). This structure was created by Eric Solary, then Laurent Lagrost became the structure&rsquo;s manager. Other groups from the UFR des Sciences de la Vie, CNRS and ENSBANA (now AgroSup) joined the unit for the 2007-2011 contract. During the second contract 2012-2016, the LNC Research Center comprised 8 distinct groups, with a total of 218 people (87 researchers\/teaching-researchers + 68 technicians\/engineers + 19 post-docs + 44 PhD students).On January 1, 2017, the unit became UMR1231. The EA4271 GAD headed by Laurence Faivre and an ERC team created by Lionel Apetoh then joined the LNC Center. The structure comprises 9 teams with 269 members (104 researchers\/teaching-researchers + 87 technicians\/engineers + 18 post-docs + 60 PhD students). On January 1, 2020, Professor Fran\u00e7ois Ghiringhelli became the unit&rsquo;s director.<\/p><p>This structure generates its scientific wealth through the diversity of its themes, involving top-level, internationally-recognized researchers in fields as varied as cancer biology (C Garrido), pulmonary fibrosis (P Bonniaud), TNF signaling (O Micheau) and tumor immunology (F Ghiringhelli), Lipid metabolism and stress (L Lagrost and D Masson), apolipoprotein pharmacokinetics and dynamics, digestive cancer epidemiology and hematology (C Lepage, M Maynadie), developmental genetics (L Faivre and C Thauvin), mouse neurogenetics (B Yalcin), translational hematology (M Callanan and L Delva).<\/p><p>The Center has been renewed for a further 4 years to January 1, 2024, and has changed its name to <strong>CTM: Center for Translational and Molecular Medicine<\/strong>. It comprises 9 teams, with the creation of a new team focused on death receptor signaling, headed by Olivier Micheau. The structure currently comprises 9 teams with a total of 337 staff (147 researchers\/teaching-researchers, 110 technicians\/engineers, 12 post-docs and 68 PhD students).<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-90b315e\" data-id=\"90b315e\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-45cdfa6 elementor-widget elementor-widget-image\" data-id=\"45cdfa6\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"1013\" height=\"1024\" src=\"https:\/\/ctm.ube.fr\/wp-content\/uploads\/2023\/08\/CTM-LOGO-_2_-1-1013x1024.png\" class=\"attachment-large size-large wp-image-2232\" alt=\"\" srcset=\"https:\/\/ctm.ube.fr\/wp-content\/uploads\/2023\/08\/CTM-LOGO-_2_-1-1013x1024.png 1013w, https:\/\/ctm.ube.fr\/wp-content\/uploads\/2023\/08\/CTM-LOGO-_2_-1-297x300.png 297w, https:\/\/ctm.ube.fr\/wp-content\/uploads\/2023\/08\/CTM-LOGO-_2_-1-768x776.png 768w, https:\/\/ctm.ube.fr\/wp-content\/uploads\/2023\/08\/CTM-LOGO-_2_-1-1520x1536.png 1520w\" sizes=\"(max-width: 1013px) 100vw, 1013px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f8a85a1 elementor-widget elementor-widget-image\" data-id=\"f8a85a1\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"1024\" height=\"1024\" src=\"https:\/\/ctm.ube.fr\/wp-content\/uploads\/2023\/08\/FGhiringhelli-web-1024x1024.jpg\" class=\"attachment-large size-large wp-image-2190\" alt=\"\" srcset=\"https:\/\/ctm.ube.fr\/wp-content\/uploads\/2023\/08\/FGhiringhelli-web-1024x1024.jpg 1024w, https:\/\/ctm.ube.fr\/wp-content\/uploads\/2023\/08\/FGhiringhelli-web-300x300.jpg 300w, https:\/\/ctm.ube.fr\/wp-content\/uploads\/2023\/08\/FGhiringhelli-web-150x150.jpg 150w, https:\/\/ctm.ube.fr\/wp-content\/uploads\/2023\/08\/FGhiringhelli-web-768x768.jpg 768w, https:\/\/ctm.ube.fr\/wp-content\/uploads\/2023\/08\/FGhiringhelli-web.jpg 1080w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-252b364 elementor-section-full_width elementor-section-stretched elementor-section-height-default elementor-section-height-default\" data-id=\"252b364\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;,&quot;stretch_section&quot;:&quot;section-stretched&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-e31a04c\" data-id=\"e31a04c\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-a071adf elementor-widget elementor-widget-accordion\" data-id=\"a071adf\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"accordion.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-accordion\">\n\t\t\t\t\t\t\t<div class=\"elementor-accordion-item\">\n\t\t\t\t\t<div id=\"elementor-tab-title-1681\" class=\"elementor-tab-title\" data-tab=\"1\" role=\"button\" aria-controls=\"elementor-tab-content-1681\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon elementor-accordion-icon-left\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-closed\"><i class=\"fas fa-plus\"><\/i><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-opened\"><i class=\"fas fa-minus\"><\/i><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-accordion-title\" tabindex=\"0\">Current center configuration<\/a>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-1681\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"1\" role=\"region\" aria-labelledby=\"elementor-tab-title-1681\"><p>The scientific areas of the LNC teams during the 2024-2027 contract are:<\/p><ul style=\"list-style-position: outside; list-style-type: disc;\"><li style=\"list-style-type: none;\"><ul style=\"list-style-position: outside; list-style-type: disc;\"><li><strong><b><a style=\"font-family: Helvetica; font-weight: normal;\" href=\"https:\/\/ctm.u-bourgogne.fr\/index.php\/01-menu-anglais\/\"><b>Therapies and immune response in cancers: TIREC<\/b><\/a><\/b><\/strong><b><b>\u2013 Fran\u00e7ois Ghiringhelli<\/b><\/b><\/li><\/ul><\/li><\/ul><ul><li><b><strong><a style=\"font-family: Helvetica;\" href=\"https:\/\/ctm.u-bourgogne.fr\/index.php\/02-menu-anglais\/\">Hematopoiesis &amp; leukemogenesis gene regulation : EPI2THM<\/a>\u00a0<\/strong>\u2013 Marry Callanan<\/b><\/li><li><b><b><a href=\"https:\/\/ctm.u-bourgogne.fr\/index.php\/03-menu-anglais\/\">Heat shock proteins: cell death, cell differentiation and tumorigenic properties : HSP-PATHIES<\/a><\/b>\u00a0\u2013 Carmen Garrido<\/b><\/li><li><b><b><a href=\"https:\/\/ctm.u-bourgogne.fr\/index.php\/04-menu-anglais\/\"> Epidemiology and clinical research in digestive cancer<\/a><\/b>\u00a0\u2013 C\u00f4me Lepage<\/b><\/li><li><b><b><a href=\"https:\/\/ctm.ube.fr\/index.php\/descartes_team\/\">Death-Domain containing TNF Receptor Signal &amp; Transduction &amp; Cancer <\/a>therapies<a href=\"https:\/\/ctm.u-bourgogne.fr\/index.php\/09-menu-anglais\/\">\u00a0:\u00a0DesCarTes<\/a><\/b> \u00a0\u2013 Olivier Micheau<\/b><\/li><li><b><b><a href=\"https:\/\/www.gad-bfc.org\/\">Genetics of developmental abnormalities \u2013 GAD<\/a><\/b>\u00a0\u2013 Christel Tauvin<\/b><\/li><li><b><b><a href=\"https:\/\/ctm.u-bourgogne.fr\/index.php\/06-menu-anglais\/\">Physiopathology of dyslipidemia : PADYS<\/a><\/b>\u00a0\u2013 Bruno Verg\u00e8s<\/b><\/li><li><b><b><a href=\"https:\/\/ctm.u-bourgogne.fr\/index.php\/07-menu\/\">Detection and metabolism of lipids and food contaminants in the oro-digestive sphere: NUTOX<\/a><a href=\"http:\/\/inserm-u1231.u-bourgogne.fr\/07-menu-anglais.php\">\u2019<\/a><\/b>\u00a0\u2013 Naim Kahn<\/b><\/li><li><b><b><a href=\"https:\/\/ctm.u-bourgogne.fr\/index.php\/08-menu-anglais\/\">Lipid transfer proteins and lipoprotein metabolism : LIPNESS<\/a><\/b>\u00a0\u2013 David Masson<\/b><\/li><\/ul><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Center For Translational and Molecular Medecine Director UMR1231: Pr Fran\u00e7ois GHIRINGHELLI Deputy Director UMR1231: Pr Dominique DELMAS History, structure and location of the unit The Centre de Recherche UMR1231- LNC was originally created as UMR866 \u00ab\u00a0Lipids, Nutrition, Cancer-LNC\u00a0\u00bb on January 1, 2007, and grew out of a joint program by several groups that led to &#8230; <a title=\"Presentation\" class=\"read-more\" href=\"https:\/\/ctm.ube.fr\/index.php\/presentation-english\/\" aria-label=\"En savoir plus sur Presentation\">Lire la suite<\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-2629","page","type-page","status-publish"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/ctm.ube.fr\/index.php\/wp-json\/wp\/v2\/pages\/2629","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ctm.ube.fr\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/ctm.ube.fr\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/ctm.ube.fr\/index.php\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/ctm.ube.fr\/index.php\/wp-json\/wp\/v2\/comments?post=2629"}],"version-history":[{"count":80,"href":"https:\/\/ctm.ube.fr\/index.php\/wp-json\/wp\/v2\/pages\/2629\/revisions"}],"predecessor-version":[{"id":6753,"href":"https:\/\/ctm.ube.fr\/index.php\/wp-json\/wp\/v2\/pages\/2629\/revisions\/6753"}],"wp:attachment":[{"href":"https:\/\/ctm.ube.fr\/index.php\/wp-json\/wp\/v2\/media?parent=2629"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}