{"id":3494,"date":"2023-12-08T14:24:10","date_gmt":"2023-12-08T14:24:10","guid":{"rendered":"https:\/\/ctm.u-bourgogne.fr\/?page_id=3494"},"modified":"2026-03-10T18:34:13","modified_gmt":"2026-03-10T18:34:13","slug":"labcom_iam-it","status":"publish","type":"page","link":"https:\/\/ctm.ube.fr\/index.php\/labcom_iam-it\/","title":{"rendered":"Labcom_IAM-IT"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"3494\" class=\"elementor elementor-3494\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-ce8a8ef elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"ce8a8ef\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-25 elementor-top-column elementor-element elementor-element-dd933d8\" data-id=\"dd933d8\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-c31746f elementor-widget elementor-widget-heading\" data-id=\"c31746f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Laboratoire commun IAM-IT<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-25 elementor-top-column elementor-element elementor-element-fb5d69f\" data-id=\"fb5d69f\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-25 elementor-top-column elementor-element elementor-element-a0ed02c\" data-id=\"a0ed02c\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-393e22d elementor-widget elementor-widget-heading\" data-id=\"393e22d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">English version<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-25 elementor-top-column elementor-element elementor-element-cc4bb56\" data-id=\"cc4bb56\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-7ee1fca elementor-widget__width-initial elementor-view-default elementor-widget elementor-widget-icon\" data-id=\"7ee1fca\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"icon.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-icon-wrapper\">\n\t\t\t<a class=\"elementor-icon\" href=\"https:\/\/ctm.u-bourgogne.fr\/index.php\/labcom_iam-it_en\/\">\n\t\t\t<i aria-hidden=\"true\" class=\"fas fa-flag-usa\"><\/i>\t\t\t<\/a>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-1b324c1 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"1b324c1\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-16c843e\" data-id=\"16c843e\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-71bef45 elementor-widget elementor-widget-image\" data-id=\"71bef45\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"100\" height=\"100\" src=\"https:\/\/ctm.ube.fr\/wp-content\/uploads\/2023\/12\/logo-iam-it-web.svg\" class=\"attachment-1536x1536 size-1536x1536 wp-image-3836\" alt=\"\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-3a909ca elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"3a909ca\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-8bbb7f1\" data-id=\"8bbb7f1\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-04155cd elementor-section-full_width elementor-section-content-space-evenly elementor-section-height-default elementor-section-height-default\" data-id=\"04155cd\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-narrow\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-5c904c7\" data-id=\"5c904c7\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-7a29007 elementor-arrows-position-inside elementor-pagination-position-outside elementor-widget elementor-widget-image-carousel\" data-id=\"7a29007\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;slides_to_show&quot;:&quot;5&quot;,&quot;navigation&quot;:&quot;both&quot;,&quot;autoplay&quot;:&quot;yes&quot;,&quot;pause_on_hover&quot;:&quot;yes&quot;,&quot;pause_on_interaction&quot;:&quot;yes&quot;,&quot;autoplay_speed&quot;:5000,&quot;infinite&quot;:&quot;yes&quot;,&quot;speed&quot;:500}\" data-widget_type=\"image-carousel.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-image-carousel-wrapper swiper\" role=\"region\" aria-roledescription=\"carousel\" aria-label=\"Carrousel d\u2019images\" dir=\"ltr\">\n\t\t\t<div class=\"elementor-image-carousel swiper-wrapper\" aria-live=\"off\">\n\t\t\t\t\t\t\t\t<div class=\"swiper-slide\" role=\"group\" aria-roledescription=\"slide\" aria-label=\"1 sur 9\"><figure class=\"swiper-slide-inner\"><img decoding=\"async\" class=\"swiper-slide-image\" src=\"https:\/\/ctm.ube.fr\/wp-content\/uploads\/2023\/12\/COVID-298x300.jpg\" alt=\"INFECTIOUS DISEASE\" \/><\/figure><\/div><div class=\"swiper-slide\" role=\"group\" aria-roledescription=\"slide\" aria-label=\"2 sur 9\"><figure class=\"swiper-slide-inner\"><img decoding=\"async\" class=\"swiper-slide-image\" src=\"https:\/\/ctm.ube.fr\/wp-content\/uploads\/2023\/12\/96wellplate-assay-1-300x291.jpg\" alt=\"96 WELL PLATE ASSAY\" \/><\/figure><\/div><div class=\"swiper-slide\" role=\"group\" aria-roledescription=\"slide\" aria-label=\"3 sur 9\"><figure class=\"swiper-slide-inner\"><img decoding=\"async\" class=\"swiper-slide-image\" src=\"https:\/\/ctm.ube.fr\/wp-content\/uploads\/2023\/12\/antibody-298x300.jpg\" alt=\"ANTIBODY\" \/><\/figure><\/div><div class=\"swiper-slide\" role=\"group\" aria-roledescription=\"slide\" aria-label=\"4 sur 9\"><figure class=\"swiper-slide-inner\"><img decoding=\"async\" class=\"swiper-slide-image\" src=\"https:\/\/ctm.ube.fr\/wp-content\/uploads\/2023\/12\/ASSAY2-300x295.jpg\" alt=\"SAMPLES\" \/><\/figure><\/div><div class=\"swiper-slide\" role=\"group\" aria-roledescription=\"slide\" aria-label=\"5 sur 9\"><figure class=\"swiper-slide-inner\"><img decoding=\"async\" class=\"swiper-slide-image\" src=\"https:\/\/ctm.ube.fr\/wp-content\/uploads\/2023\/12\/EM2-300x295.jpg\" alt=\"EPITOPE MAPPING &amp;2 (AI GENERATED)\" \/><\/figure><\/div><div class=\"swiper-slide\" role=\"group\" aria-roledescription=\"slide\" aria-label=\"6 sur 9\"><figure class=\"swiper-slide-inner\"><img decoding=\"async\" class=\"swiper-slide-image\" src=\"https:\/\/ctm.ube.fr\/wp-content\/uploads\/2023\/12\/EM3-300x294.jpg\" alt=\"EPITOPE MAPPING &amp;3 (AI GENERATED)\" \/><\/figure><\/div><div class=\"swiper-slide\" role=\"group\" aria-roledescription=\"slide\" aria-label=\"7 sur 9\"><figure class=\"swiper-slide-inner\"><img decoding=\"async\" class=\"swiper-slide-image\" src=\"https:\/\/ctm.ube.fr\/wp-content\/uploads\/2023\/12\/green-Cells-296x300.jpg\" alt=\"GREEN CELLS\" \/><\/figure><\/div><div class=\"swiper-slide\" role=\"group\" aria-roledescription=\"slide\" aria-label=\"8 sur 9\"><figure class=\"swiper-slide-inner\"><img decoding=\"async\" class=\"swiper-slide-image\" src=\"https:\/\/ctm.ube.fr\/wp-content\/uploads\/2023\/12\/EM1-1-300x298.jpg\" alt=\"EPITOPE MAPPING &amp;1 (AI GENERATED)\" \/><\/figure><\/div><div class=\"swiper-slide\" role=\"group\" aria-roledescription=\"slide\" aria-label=\"9 sur 9\"><figure class=\"swiper-slide-inner\"><img decoding=\"async\" class=\"swiper-slide-image\" src=\"https:\/\/ctm.u-bourgogne.fr\/wp-content\/uploads\/2024\/12\/movie1.mp4\" alt=\"\" \/><\/figure><\/div>\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"elementor-swiper-button elementor-swiper-button-prev\" role=\"button\" tabindex=\"0\">\n\t\t\t\t\t\t<i aria-hidden=\"true\" class=\"eicon-chevron-left\"><\/i>\t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"elementor-swiper-button elementor-swiper-button-next\" role=\"button\" tabindex=\"0\">\n\t\t\t\t\t\t<i aria-hidden=\"true\" class=\"eicon-chevron-right\"><\/i>\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t<div class=\"swiper-pagination\"><\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-c468c53 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"c468c53\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-0b7aa60\" data-id=\"0b7aa60\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-b860525 elementor-widget__width-initial elementor-widget elementor-widget-text-editor\" data-id=\"b860525\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h5><i>\u25b6\ufe0e <strong>CONTEXTE ET VISION \u00a0\u00a0<\/strong><\/i><\/h5><h5>Dans un monde ou l&rsquo;immunoth\u00e9rapie red\u00e9finit le traitement du cancer, notre\u00a0<span style=\"color: #99ccff;\"><strong> laboratoire commun <\/strong><\/span><span style=\"color: #99ccff;\"><strong>IAM-IT<\/strong> <\/span>(Ing\u00e9nierie des Anticorps Monoclonaux Innovants \u00e0 vis\u00e9e th\u00e9rapeutique) se positionne \u00e0 la pointe de cette r\u00e9volution. Face \u00e0 des d\u00e9fis croissants comme l&rsquo;inflammation chronique et les infections, notamment r\u00e9v\u00e9l\u00e9es par la pand\u00e9mie de COVID-19, nous nous engageons \u00e0 d\u00e9velopper des anticorps monoclonaux (AcM) innovants. Notre mission ne se limite pas \u00e0 la cr\u00e9ation de th\u00e9rapies; nous proposons \u00e9galement des outils de caract\u00e9risation avanc\u00e9s pour optimiser leur efficacit\u00e9.<\/h5><h5><strong>L&rsquo;expertise d&rsquo;IAM-IT<\/strong> combine le savoir-faire de <a href=\"https:\/\/www.covalab.com\/eu\/\">COVALAB<\/a> et due l&rsquo;<a href=\"https:\/\/ctm.ube.fr\/index.php\/equipe-descartes\/\">\u00e9quipe DesCarTes<\/a> du <a href=\"https:\/\/ctm.ube.fr\">CTM<\/a> dans les domaines de la biologie mol\u00e9culaire, de l&rsquo;immunologie et de la vectorisation des drogues. Nous explorons notamment les immunoconjugu\u00e9s (ADC), fusionnant science et innovation pour offrir des solutions th\u00e9rapeutiques sur mesure.<\/h5><h5><i>\u00a0\u25b6\ufe0e <\/i><strong>M\u00c9THODOLOGIE ET INNOVATIONS<\/strong><\/h5><h5>Approche Pionni\u00e8re en collaboration avec <a href=\"https:\/\/www.covalab.com\/eu\/\">COVALAB<\/a>, nous avons d\u00e9velopp\u00e9 une m\u00e9thode d&rsquo;immunisation unique qui permet de g\u00e9n\u00e9rer des AcMs capables de reconna\u00eetre leurs cibles dans leur conformation native <span style=\"font-family: inherit; font-style: inherit;\">(<\/span><a style=\"font-family: inherit; font-style: inherit;\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30718507\/\">Dubuisson<\/a><span style=\"font-family: inherit; font-style: inherit;\"> et al. 2019)<\/span><span style=\"font-family: inherit; font-style: inherit;\">. Gr\u00e2ce \u00e0 nos outils mol\u00e9culaires, incluant un syst\u00e8me avanc\u00e9 d&rsquo;\u00e9dition de <\/span><span style=\"font-family: inherit; font-style: inherit;\">g\u00e8ne (<\/span><a style=\"font-family: inherit; font-style: inherit;\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37156748\/\">Radoua<\/a><span style=\"font-family: inherit; font-style: inherit;\"> et al. 2023 and <a href=\"https:\/\/www.sciencedirect.com\/science\/chapter\/bookseries\/pii\/S0091679X26000701?via%3Dihub\">Radoua<\/a> et al. 2026)<\/span><span style=\"font-family: inherit; font-style: inherit;\">, nous pouvons modifier rapidement les antig\u00e8nes. Cela nous permet de cr\u00e9er des AcMs dot\u00e9s de propri\u00e9t\u00e9s pharmacologiques distinctes et de cartographier leur reconnaissance \u00e9pitopique pour mieux les discriminer. \u00a0\u00a0<\/span><\/h5><h5>\u25b6\ufe0e <strong>RESULTATS MAJEURS DU PROJET<\/strong><\/h5><h5>Labelis\u00e9 par le p\u00f4le de comp\u00e9titivit\u00e9 <a href=\"https:\/\/lyonbiopole.com\">Lyonbiop\u00f4le<\/a>, et bas\u00e9 \u00e0 <a href=\"https:\/\/www.destinationdijon.com\">Dijon<\/a>, notre projet a abouti au d\u00e9veloppement d\u2019AcMs avec des propri\u00e9t\u00e9s anticanc\u00e9reuses ciblant les r\u00e9cepteurs de la famille du TNF, ainsi qu\u2019anti-infectieuses, ciblant la prot\u00e9ine SPIKE du COVID. Nos approches innovantes de cartographie \u00e9pitopique permettent une caract\u00e9risation pr\u00e9cise de ces anticorps, offrant ainsi une flexibilit\u00e9 pour contourner d\u2019\u00e9ventuelles r\u00e9sistances dues \u00e0 des mutations.\u00a0<\/h5><h5><i>\u25b6\ufe0e <strong>VALIDATION ET PERSPECTIVES<\/strong><\/i><\/h5><h5>Nous avons valid\u00e9 notre approche de cartographie \u00e9pitopique \u00e0 travers la mod\u00e9lisation d\u2019un anticorps anti-DR5 (voir ci dessous) ou anti-SPIKE (non montr\u00e9), dont la structure a \u00e9t\u00e9 cristallis\u00e9e et test\u00e9e par simulation mol\u00e9culaire dynamique. Cette m\u00e9thode, adaptable \u00e0 d&rsquo;autres cibles membranaires, ouvre la voie \u00e0 des traitements personnalis\u00e9s et efficaces.<\/h5><p><img fetchpriority=\"high\" decoding=\"async\" class=\"aligncenter wp-image-7039 size-full\" src=\"https:\/\/ctm.ube.fr\/wp-content\/uploads\/2026\/03\/Figure-Labcom-Website.jpg\" alt=\"\" width=\"2000\" height=\"1163\" srcset=\"https:\/\/ctm.ube.fr\/wp-content\/uploads\/2026\/03\/Figure-Labcom-Website.jpg 2000w, https:\/\/ctm.ube.fr\/wp-content\/uploads\/2026\/03\/Figure-Labcom-Website-300x174.jpg 300w, https:\/\/ctm.ube.fr\/wp-content\/uploads\/2026\/03\/Figure-Labcom-Website-1024x595.jpg 1024w, https:\/\/ctm.ube.fr\/wp-content\/uploads\/2026\/03\/Figure-Labcom-Website-768x447.jpg 768w, https:\/\/ctm.ube.fr\/wp-content\/uploads\/2026\/03\/Figure-Labcom-Website-1536x893.jpg 1536w\" sizes=\"(max-width: 2000px) 100vw, 2000px\" \/><\/p><p><strong><span style=\"font-family: inherit;\">Validation de l&rsquo;approche de cartographie <\/span>\u00e9pitopique<\/strong> (A) et (B) par la mod\u00e9lisation d&rsquo;un anticoprs anti-DR5 connu et dont la structure a \u00e9t\u00e9 cristallis\u00e9e et test\u00e9e par simulation mol\u00e9culaire dynamiques (C). <span lang=\"EN-US\">Le r\u00e9cepteur DR5 est illustr\u00e9 en Jaune\/vert, les chaines l\u00e9g\u00e8res L(LC) et lourdes (HC) de l&rsquo;anticorps anti-DR5 sont \u00a0repr\u00e9sent\u00e9es en rouge et bleu, respectivement. (D) Sch\u00e9ma de cartographie montrant les interactions les plus fortes (liaisons salines, hydrog\u00e8nes, etc&#8230;), d\u00e9duites de la simulation.<\/span><\/p><div>Cette approche est adaptable \u00e0 d&rsquo;autres cibles membranaires.<\/div><div>\u00a0<\/div><div><h3>\ud83d\udcde Contactez-nous<\/h3><\/div><div><ul><li><strong>Caract\u00e9risation de vos anticorps<\/strong> : Si vous souhaitez caract\u00e9riser vos anticorps anti-SPIKE, anti-DR4 ou DR5, nous sommes \u00e0 votre disposition.<\/li><li><strong>D\u00e9veloppement de tests compagnons<\/strong> : Pour d\u00e9velopper un test compagnon d&rsquo;\u00e9pitope mapping, permettant de caract\u00e9riser votre anticorps, n&rsquo;h\u00e9sitez pas \u00e0 nous contacter.<\/li><\/ul><\/div><p>\ud83d\udce7 <strong>Email<\/strong> : omicheau(at)u-bourgogne.fr<\/p><div style=\"padding-left: 40px;\">\u00a0<\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-84aeb1e elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"84aeb1e\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-0099c74\" data-id=\"0099c74\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-d4f49c5 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"d4f49c5\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-f72d93f\" data-id=\"f72d93f\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-0255d11 elementor-widget elementor-widget-heading\" data-id=\"0255d11\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\"><a href=\"https:\/\/www.covalab.com\/eu\/\">ANR 22-LCV-1-0005-01\n\n<\/a><\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-397d602 elementor-widget__width-initial elementor-widget elementor-widget-image\" data-id=\"397d602\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"320\" height=\"320\" src=\"https:\/\/ctm.ube.fr\/wp-content\/uploads\/2023\/08\/anr.png\" class=\"attachment-medium_large size-medium_large wp-image-2176\" alt=\"\" srcset=\"https:\/\/ctm.ube.fr\/wp-content\/uploads\/2023\/08\/anr.png 320w, https:\/\/ctm.ube.fr\/wp-content\/uploads\/2023\/08\/anr-300x300.png 300w, https:\/\/ctm.ube.fr\/wp-content\/uploads\/2023\/08\/anr-150x150.png 150w\" sizes=\"(max-width: 320px) 100vw, 320px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-0d647ae\" data-id=\"0d647ae\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-6c4bfb7 elementor-widget elementor-widget-heading\" data-id=\"6c4bfb7\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h6 class=\"elementor-heading-title elementor-size-default\">Annonces du soutien financier ANR LAbCom IAM-IT en 2022<\/h6>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-859b932 elementor-widget elementor-widget-heading\" data-id=\"859b932\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h6 class=\"elementor-heading-title elementor-size-default\"><a href=\"https:\/\/www.mabdesign.fr\/covalab-laureat-de-labcom-2022\/\">mabdesign \n<\/a><\/h6>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-df241eb elementor-widget elementor-widget-heading\" data-id=\"df241eb\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h5 class=\"elementor-heading-title elementor-size-default\"><a href=\"https:\/\/www.labex-lipstic.fr\/le-lnc-umr1231-ctm-est-laureat-de-lappel-a-projets-labcom-aap-anr-2022\/\">Labex LipSTIC <\/a><\/h5>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3a6ce58 elementor-widget elementor-widget-heading\" data-id=\"3a6ce58\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h6 class=\"elementor-heading-title elementor-size-default\"><a href=\"https:\/\/www.covalab.com\/labcom2022\">Covalab<\/a><\/h6>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-37e81b2 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"37e81b2\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-3269755\" data-id=\"3269755\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-c2d2487 elementor-widget elementor-widget-heading\" data-id=\"c2d2487\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Partenaires : <\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ffd9cca elementor-widget__width-initial elementor-widget elementor-widget-image\" data-id=\"ffd9cca\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.covalab.com\/eu\/\" target=\"_blank\">\n\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"420\" src=\"https:\/\/ctm.ube.fr\/wp-content\/uploads\/2023\/12\/logo_covalab_rd_2012_green-1024x420.jpg\" class=\"attachment-large size-large wp-image-3600\" alt=\"\" srcset=\"https:\/\/ctm.ube.fr\/wp-content\/uploads\/2023\/12\/logo_covalab_rd_2012_green-1024x420.jpg 1024w, https:\/\/ctm.ube.fr\/wp-content\/uploads\/2023\/12\/logo_covalab_rd_2012_green-300x123.jpg 300w, https:\/\/ctm.ube.fr\/wp-content\/uploads\/2023\/12\/logo_covalab_rd_2012_green-768x315.jpg 768w, https:\/\/ctm.ube.fr\/wp-content\/uploads\/2023\/12\/logo_covalab_rd_2012_green-1536x630.jpg 1536w, https:\/\/ctm.ube.fr\/wp-content\/uploads\/2023\/12\/logo_covalab_rd_2012_green.jpg 1816w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/>\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-66 elementor-top-column elementor-element elementor-element-62d77eb\" data-id=\"62d77eb\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-fc4d6ff elementor-widget__width-initial elementor-widget elementor-widget-image\" data-id=\"fc4d6ff\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/ctm.u-bourgogne.fr\/index.php\/09-menu\/\">\n\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"100\" height=\"100\" src=\"https:\/\/ctm.ube.fr\/wp-content\/uploads\/2023\/12\/logo-descartes.svg\" class=\"attachment-large size-large wp-image-3803\" alt=\"logo d&apos;\u00e9quipe\" \/>\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-0d70d32 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"0d70d32\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-4ab81ed\" data-id=\"4ab81ed\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-6983faa elementor-widget elementor-widget-heading\" data-id=\"6983faa\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h6 class=\"elementor-heading-title elementor-size-default\">MISE \u00c0 JOUR LE 10 Mars 2026<\/h6>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Laboratoire commun IAM-IT English version \u25b6\ufe0e CONTEXTE ET VISION \u00a0\u00a0 Dans un monde ou l&rsquo;immunoth\u00e9rapie red\u00e9finit le traitement du cancer, notre\u00a0 laboratoire commun IAM-IT (Ing\u00e9nierie des Anticorps Monoclonaux Innovants \u00e0 vis\u00e9e th\u00e9rapeutique) se positionne \u00e0 la pointe de cette r\u00e9volution. Face \u00e0 des d\u00e9fis croissants comme l&rsquo;inflammation chronique et les infections, notamment r\u00e9v\u00e9l\u00e9es par la &#8230; <a title=\"Labcom_IAM-IT\" class=\"read-more\" href=\"https:\/\/ctm.ube.fr\/index.php\/labcom_iam-it\/\" aria-label=\"En savoir plus sur Labcom_IAM-IT\">Lire la suite<\/a><\/p>\n","protected":false},"author":27,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-3494","page","type-page","status-publish"],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 5.0.4 - aioseo.com -->\n\t<meta name=\"description\" content=\"Laboratoire commun IAM-IT English version \u25b6\ufe0e CONTEXTE ET VISION Dans un monde ou l\u2019immunoth\u00e9rapie red\u00e9finit le traitement du cancer, notre laboratoire commun IAM-IT (Ing\u00e9nierie des Anticorps Monoclonaux Innovants \u00e0 vis\u00e9e th\u00e9rapeutique) se positionne \u00e0 la pointe de cette r\u00e9volution. 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