{"id":4915,"date":"2023-08-10T17:50:33","date_gmt":"2023-08-10T17:50:33","guid":{"rendered":"https:\/\/ctm.u-bourgogne.fr\/?p=4915"},"modified":"2024-01-26T18:00:37","modified_gmt":"2024-01-26T18:00:37","slug":"first-line-durvalumab-and-tremelimumab-with-chemotherapy-in-ras-mutated-metastatic-colorectal-cancer-a-phase-1b-2-trial","status":"publish","type":"post","link":"https:\/\/ctm.ube.fr\/index.php\/2023\/08\/10\/first-line-durvalumab-and-tremelimumab-with-chemotherapy-in-ras-mutated-metastatic-colorectal-cancer-a-phase-1b-2-trial\/","title":{"rendered":"First-line durvalumab and tremelimumab with chemotherapy in RAS-mutated metastatic colorectal cancer: a phase 1b\/2 trial"},"content":{"rendered":"\n<p>Thibaudin M, Fumet JD, Chibaudel B, Bennouna J, Borg C, Martin-Babau J, Cohen R, Fonck M, Taieb J, Limagne E, Blanc J, Ballot E, Hampe L, Bon M, Daumoine S, Peroz M, Mananet H, Derang\u00e8re V, Boidot R, Michaud HA, Laheurte C, Adotevi O, Bertaut A, Truntzer C, Ghiringhelli F. First-line durvalumab and tremelimumab with chemotherapy in RAS-mutated metastatic colorectal cancer: a phase 1b\/2 trial. Nat Med. 2023 Aug;29(8):2087-2098. doi: <a href=\"https:\/\/www.nature.com\/articles\/s41591-023-02497-z\" title=\"\">10.1038\/s41591-023-02497-z<\/a>. Epub 2023 Aug 10. PMID: <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37563240\/\" title=\"\">37563240<\/a>; PMCID: <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC10427431\/\" title=\"\">PMC10427431<\/a>.<\/p>\n\n\n\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37563240\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/37563240\/<\/a><\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img fetchpriority=\"high\" decoding=\"async\" width=\"720\" height=\"816\" src=\"https:\/\/ctm.u-bourgogne.fr\/wp-content\/uploads\/2024\/01\/Image2.png\" alt=\"\" class=\"wp-image-4916\" srcset=\"https:\/\/ctm.ube.fr\/wp-content\/uploads\/2024\/01\/Image2.png 720w, https:\/\/ctm.ube.fr\/wp-content\/uploads\/2024\/01\/Image2-265x300.png 265w\" sizes=\"(max-width: 720px) 100vw, 720px\" \/><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>Thibaudin M, Fumet JD, Chibaudel B, Bennouna J, Borg C, Martin-Babau J, Cohen R, Fonck M, Taieb J, Limagne E, Blanc J, Ballot E, Hampe L, Bon M, Daumoine S, Peroz M, Mananet H, Derang\u00e8re V, Boidot R, Michaud HA, Laheurte C, Adotevi O, Bertaut A, Truntzer C, Ghiringhelli F. First-line durvalumab and tremelimumab with &#8230; <a title=\"First-line durvalumab and tremelimumab with chemotherapy in RAS-mutated metastatic colorectal cancer: a phase 1b\/2 trial\" class=\"read-more\" href=\"https:\/\/ctm.ube.fr\/index.php\/2023\/08\/10\/first-line-durvalumab-and-tremelimumab-with-chemotherapy-in-ras-mutated-metastatic-colorectal-cancer-a-phase-1b-2-trial\/\" aria-label=\"En savoir plus sur First-line durvalumab and tremelimumab with chemotherapy in RAS-mutated metastatic colorectal cancer: a phase 1b\/2 trial\">Lire la suite<\/a><\/p>\n","protected":false},"author":23,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3],"tags":[],"class_list":["post-4915","post","type-post","status-publish","format-standard","hentry","category-publication"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/ctm.ube.fr\/index.php\/wp-json\/wp\/v2\/posts\/4915","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ctm.ube.fr\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/ctm.ube.fr\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/ctm.ube.fr\/index.php\/wp-json\/wp\/v2\/users\/23"}],"replies":[{"embeddable":true,"href":"https:\/\/ctm.ube.fr\/index.php\/wp-json\/wp\/v2\/comments?post=4915"}],"version-history":[{"count":2,"href":"https:\/\/ctm.ube.fr\/index.php\/wp-json\/wp\/v2\/posts\/4915\/revisions"}],"predecessor-version":[{"id":4919,"href":"https:\/\/ctm.ube.fr\/index.php\/wp-json\/wp\/v2\/posts\/4915\/revisions\/4919"}],"wp:attachment":[{"href":"https:\/\/ctm.ube.fr\/index.php\/wp-json\/wp\/v2\/media?parent=4915"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ctm.ube.fr\/index.php\/wp-json\/wp\/v2\/categories?post=4915"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ctm.ube.fr\/index.php\/wp-json\/wp\/v2\/tags?post=4915"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}