CTM

Pr Philippe Froguel Monday May the 5th 2025

Precision Metabolic Medicine: new insight and hopes

Type 2 diabetes and obesity are multifactorial systemic conditions associated with serious co-

morbidities. They both have a strong genetic and epigenetic basis that have been in part

elucidated by both Genome Wide Association Studies (for the polygenic background) and by

genome sequencing (for rare variants causing monogenic and oligogenic metabolic diseases).

Taking into account the genomic information does not only improve our knowledge of the

pathophysiology but also opens avenues towards more personalized diabetes care.

Key words: Diabetes, obesity, genomics, DNA sequencing

Link to the seminar which will take place at the UFR Science de Santé, Amphi Martin 1 pm

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